abstract：:This study aimed to evaluate the clinical characteristics and surgical treatment of bicuspid aortic valve (BAV) infective endocarditis (IE) compared with tricuspid aortic valve (TAV) IE in China.The relevant pre-, intra- and post-operative materials of all IE patients undergoing cardiac surgery in our center between J...

journal_title：International heart journal

authors： Chen J,Lu S,Hu K,Yang Z,Pan S,Hong T,Wang C

更新日期：2017-04-06 00:00:00

abstract：:Atherosclerosis is a multifactorial vascular disease characterized by formation of inflammatory lesions. Secretory phospholipase A2, group IIA (sPLA2-IIA) is involved in this process and plays a critical role. However, the exact role of sPLA2-IIA in cardiovascular inflammation is more complicated and remains unclear. ...

journal_title：International heart journal

authors： Xie Q,Zhang D

更新日期：2017-02-07 00:00:00

abstract：:The vasopressin receptor 2 (V2) receptor antagonist tolvaptan is an aquaretic agent that has been approved for heart failure patients with volume overload in Japan. In this study (SMILE study), we investigated patient characteristics and effectiveness in both a 14 days and shorter treated group (14DS) and 15 days and ...

journal_title：International heart journal

authors： Kinugawa K,Inomata T,Sato N,Yasuda M,Shimakawa T,Bando K,Fukuta Y

更新日期：2017-02-07 00:00:00

abstract：:A 68-year-old female with acute coronary syndrome was transferred to our hospital. Emergency coronary angiography showed 90% stenosis with severe calcification in the proximal right coronary artery (RCA). Intravascular ultrasound (IVUS) images were obtained and showed circumferential heavy calcification without any ev...

journal_title：International heart journal

authors： Goryo Y,Kume T,Kobayashi Y,Okamoto H,Kawamura A,Fukuhara K,Koyama T,Yamada R,Imai K,Neishi Y,Uemura S

更新日期：2017-02-07 00:00:00

abstract：:Although some patients with fulminant myocarditis can be rescued owing to the improvements in mechanical circulatory support therapy, there are few reports providing evidence of cardiac rehabilitation during mechanical circulatory supports, particularly among pediatric patients. We treated two pediatric patients who u...

journal_title：International heart journal

authors： Amao R,Imamura T,Sawada Y,Endo S,Ozaki S,Okamura K,Masuzawa A,Takaoka T,Hirata Y,Shindo T,Ono M,Haga N

更新日期：2016-12-02 00:00:00

abstract：:Direct oral anticoagulants (DOACs) have been shown to be safe and effective for the prevention of stroke in nonvalvular atrial fibrillation (NVAF) patients, however, experience with peri-AF ablation management of DOACs is scarce. This study aimed to investigate the safety and feasibility of periprocedural anticoagulat...

journal_title：International heart journal

authors： Kawabata M,Sasaki T,Maeda S,Shirai Y,Yamauchi Y,Nitta J,Goya M,Hirao K

更新日期：2016-12-02 00:00:00

abstract：:The usefulness of coronary magnetic resonance angiography (cMRA) has been reported, although the difference in the diagnostic accuracy of different protocols has not been established.We compared conventional coronary angiography (CAG) and cMRA, conducted within 6 months in 24 consecutive patients between September 201...

journal_title：International heart journal

authors： Namba Y,Fuke S,Kashihara Y,Tanaka M,Yumoto A,Saito H,Sato T

更新日期：2016-09-28 00:00:00

abstract：:Marfan syndrome (MFS) is a systemic connective tissue disorder that is caused by mutations of fibrillin-1. While MFS patients are at a high risk of periodontitis and aortic diseases, little causal information has been provided to date. To clarify the relationship, their oral condition and sinus of Valsalva (SoV) were ...

journal_title：International heart journal

authors： Suzuki J,Imai Y,Aoki M,Fujita D,Takeda N,Aoyama N,Wakayama K,Ikeda Y,Kumagai H,Akazawa H,Izumi Y,Isobe M,Komuro I,Hirata Y

更新日期：2016-07-27 00:00:00

abstract：:Sirt1 is a highly conserved nicotinamide adenine dinucleotide (NAD(+)) dependent histone deacetylase which plays an important role in heart diseases. Studies performed with Sirt1 activators indicated that it protects cells from ischemia/ reperfusion (I/R) injury. The protective effects of H2S against I/R injury also h...

journal_title：International heart journal

authors： Hu MZ,Zhou B,Mao HY,Sheng Q,Du B,Chen JL,Pang QF,Ji Y

更新日期：2016-07-27 00:00:00

abstract：:T1 or longitudinal relaxation time is one of the very fundamental magnetic resonance imaging (MRI) time constants and a tissue characterizing parameter. Only during the last decade did it become possible to quantify T1 values of the myocardium through T1 mapping. Evolving from only region of interest analysis and long...

journal_title：International heart journal

authors： Hamdy A,Kitagawa K,Ishida M,Sakuma H

更新日期：2016-07-27 00:00:00

abstract：:Vagus nerve stimulation (VNS), targeting the imbalanced autonomic nervous system, is a promising therapeutic approach for chronic heart failure (HF). Moreover, calcium cycling is an important part of cardiac excitation-contraction coupling (ECC), which also participates in the antiarrhythmic effects of VNS. We hypothe...

journal_title：International heart journal

authors： Zhang Y,Chen A,Song L,Li M,Luo Z,Zhang W,Chen Y,He B

更新日期：2016-05-25 00:00:00

abstract：:The factors responsible for the ST-T wave alternans (STTA) and associated arrhythmias during acute ischemia have not been clarified.In acutely ischemic porcine myocardium, we recorded transmural unipolar and bipolar electrocardiograms and mid-myocardial extracellular K(+) ([K(+)]e) from the center of the ischemic zone...

journal_title：International heart journal

authors： Watanabe I,Gettes LS

更新日期：2016-05-25 00:00:00

abstract：:There have been very few studies on serum biomarkers associated with hypertension in disaster situations. We assessed biomarkers associated with disaster-related hypertension (DRH) due to the Great East Japan Earthquake of March 2011.We collected blood samples from members of the Japan Self Defense Forces (JSDF) (n = ...

journal_title：International heart journal

authors： Shiraishi Y,Kujiraoka T,Hakuno D,Masaki N,Tokuno S,Adachi T

更新日期：2016-01-01 00:00:00

abstract：:Medical treatment for asymptomatic carotid artery stenosis (ACAS) has advanced recently. The outcomes of medical treatment and surgical treatment were evaluated to clarify the optimal treatment for ACAS.Patients with ACAS of ≥ 50% luminal narrowing underwent serial follow-up carotid artery ultrasonography for one year...

journal_title：International heart journal

authors： Sato K,Fujiyoshi K,Hoshi K,Noda C,Yamaoka-Tojo M,Ako J,Kumabe T

更新日期：2016-01-01 00:00:00

abstract：:We are pleased to announce that the following 4 articles have been selected for the the UEDA Heart Awards for the Year 2016.First PlaceDelivery of Imatinib-Incorporated Nanoparticles into Lungs Suppresses the Development of Monocrotaline-Induced Pulmonary Arterial HypertensionSatoshi Akagi, Kazufumi Nakamura, Daiji Mi...

journal_title：International heart journal

authors：

更新日期：2016-01-01 00:00:00

abstract：:An increase of pulmonary artery pressure in patients with pulmonary hypertension (PH) results in right ventricular failure and ultimately death. High-mobility group box 1 (HMGB1), a nuclear protein, acts as a pro-inflammatory cytokine by activating receptor for advanced glycation end-products (RAGE) in the extracellul...

journal_title：International heart journal

authors： Suzuki S,Nakazato K,Sugimoto K,Yoshihisa A,Yamaki T,Kunii H,Suzuki H,Saitoh S,Takeishi Y

更新日期：2016-01-01 00:00:00

abstract：:Everolimus (EVL), one of the mammalian targets of rapamycin, is a next generation immunosuppressant that may have accessory anti-proliferative effects in heart transplant (HTx) recipients. However, little is known about the clinical relationship between EVL and regression of cardiac hypertrophy. A total of 42 HTx reci...

journal_title：International heart journal

authors： Imamura T,Kinugawa K,Nitta D,Kinoshita O,Nawata K,Ono M

更新日期：2016-01-01 00:00:00

abstract：:Although calcium channel blockers (CCB) are expected to improve the augmentation index (AI) in CKD patients, the potential effect of benidipine on AI has been poorly studied.The present study aimed to compare the effect of benidipine and amlodipine in the treatment of CKD patients as measured through AI and urinary al...

journal_title：International heart journal

authors： Takayama T,Yoda S,Yajima Y,Kasamaki Y,Kunimoto S,Kanai T,Hirayama A

更新日期：2016-01-01 00:00:00

abstract：:Acute aortic dissection (AAD) is a life-threatening cardiovascular disease with high mortality. Hypertension is a well known risk factor of AAD. There have been previous reports about the association between circadian variation of blood pressure (BP) and cardiovascular events. However, little is known about the associ...

journal_title：International heart journal

authors： Seguchi M,Wada H,Sakakura K,Nakagawa T,Ibe T,Ikeda N,Sugawara Y,Ako J,Momomura S

更新日期：2015-05-13 00:00:00

abstract：:There are many published articles on the effects of the antithrombolytic function of platelet glycoprotein IIb/IIIa inhibitors (GP IIb/IIIa inhibitors) in myocardial infarction. However, few studies have explored the effects and optimal concentration of tirofibans in diminishing the extent of myocardial reperfusion in...

journal_title：International heart journal

authors： Chang ST,Chung CM,Chu CM,Yang TY,Pan KL,Hsu JT,Hsiao JF

更新日期：2015-05-13 00:00:00

abstract：:While physiological levels of nitric oxide (NO) protect the endothelium and have vasodilatory effects, excessive NO has adverse effects on the cardiovascular system. Recently, new NO-releasing pharmacodynamic hybrids of angiotensin II (Ang II) type 1 (AT1) receptor blockers (ARBs) have been developed.We analyzed wheth...

journal_title：International heart journal

authors： Yahiro E,Miura S,Suematsu Y,Matsuo Y,Arimura T,Kuwano T,Imaizumi S,Iwata A,Uehara Y,Saku K

更新日期：2015-01-01 00:00:00

abstract：:Patients with periodontal disease exhibit exacerbated atherosclerosis, aortic stiffness, or vascular endothelial dysfunction. However, in a recent scientific statement, the American Heart Association noted that neither has periodontal disease been proven to cause atherosclerotic vascular disease nor has the treatment ...

journal_title：International heart journal

authors： Hayashi S,Yamada H,Fukui M,Ito HO,Sata M

更新日期：2015-01-01 00:00:00

abstract：:Hypertrophic cardiomyopathy (HCM) has various morphological and clinical features. A decade has passed since the previous survey of the epidemiological and clinical characteristics of Japanese HCM patients. The Aichi Hypertrophic Cardiomyopathy (AHC) Registry is based on a prospective multicenter observational study o...

journal_title：International heart journal

authors： Yoshinaga M,Yoshikawa D,Ishii H,Hirashiki A,Okumura T,Kubota A,Sakai S,Harada K,Somura F,Mizuno T,Fujiwara W,Yokoi H,Hayashi M,Ishii J,Ozaki Y,Murohara T,Yoshida Y,Amano T,Izawa H

更新日期：2015-01-01 00:00:00

abstract：:Exercise capacity is lowered in patients with heart failure, which limits their daily activities and also reduces their quality of life. Furthermore, lowered exercise capacity has been well demonstrated to be closely related to the severity and prognosis of heart failure. Skeletal muscle abnormalities including abnorm...

journal_title：International heart journal

authors： Kinugawa S,Takada S,Matsushima S,Okita K,Tsutsui H

更新日期：2015-01-01 00:00:00

abstract：:Pulmonary hypertension (PH) induced by pulmonary tumor thrombotic microangiopathy (PTTM) can be fatal because its rapid progression confounds diagnosis, and it is difficult to control with therapy. Here we describe a woman with symptomatic PTTM-PH accompanying gastric cancer that was suspected from perfusion scintigra...

journal_title：International heart journal

authors： Minatsuki S,Miura I,Yao A,Abe H,Muraoka H,Tanaka M,Imamura T,Inaba T,Maki H,Hatano M,Kinugawa K,Yao T,Fukayama M,Nagai R,Komuro I

更新日期：2015-01-01 00:00:00

abstract：:Decreased Transthyretin (TTR) can be observed in heart failure patients with malnutrition evaluated by the Mini Nutritional Assessment (MNA). This study investigated whether a combination of different nutritional assessment methods would be useful for assessing prognosis in patients with acute decompensated heart fail...

journal_title：International heart journal

authors： Suzuki N,Kida K,Suzuki K,Harada T,Akashi YJ

更新日期：2015-01-01 00:00:00

abstract：:High sensitive C-reactive protein (hs-CRP) levels are associated with short- and long-term mortality in patients with acute coronary syndrome (ACS). We investigated whether baseline hs-CRP levels are associated with burden of coronary atherosclerosis assessed by SYNTAX score (SXScore).We enrolled 321 patients with ACS...

journal_title：International heart journal

authors： Karadeniz M,Duran M,Akyel A,Yarlıoğlueş M,Öcek AH,Çelik İE,Kılıç A,Yalcin AA,Ergün G,Murat SN

更新日期：2015-01-01 00:00:00

abstract：:Worsening of mitral regurgitation (MR) is sometimes observed after closure of an atrial septal defect (ASD). However, since the mechanism of this deterioration remains unclear, the aim of our study was to investigate the effect of left (LV) and right ventricular (RV) geometry on MR after transcatheter closure of ASD.W...

journal_title：International heart journal

authors： Hiraishi M,Tanaka H,Motoji Y,Sawa T,Tsuji T,Miyoshi T,Imanishi J,Kaneko A,Matsumoto K,Shinke T,Hirata K

更新日期：2015-01-01 00:00:00

abstract：:In this study we aimed to investigate whether there is an association between the neutrophil to lymphocyte ratio (NLR) and severity of coronary artery disease (CAD) in patients with non-ST segment elevation myocardial infarction (NSTEMI) using the SYNTAX score (SXscore). A total of 414 patients with NSTEMI who underwe...

journal_title：International heart journal

authors： Kurtul S,Sarli B,Baktir AO,Demirbas M,Saglam H,Doğan Y,Sahin O,Akpek M,Odabas H,Arinc H,Kaya MG

更新日期：2015-01-01 00:00:00

abstract：:This study aimed to evaluate the potential associations of intermediate monocytes (CD14(++)CD16(+)) with myocardial remodelling in ST segment elevation myocardial infarction (STEMI) patients with diabetes.A total of 67 STEMI patients with diabetes were enrolled. The control group consisted of 65 STEMI patients without...

journal_title：International heart journal

authors： Lu W,Zhang Z,Fu C,Ma G

更新日期：2015-01-01 00:00:00

abstract：:Since diabetes mellitus (DM) is the most common cause of heart failure (HF), it is critically important to clarify whether incretin hormones including glucagon-like peptide-1 (GLP-1), which play an important role in blood glucose control, mediate cardioprotection. There are many lines of basic research evidence indica...

journal_title：International heart journal

authors： Takahashi A,Ihara M,Yamazaki S,Asanuma H,Asakura M,Kitakaze M

更新日期：2015-01-01 00:00:00

abstract：:Comparison of the prognostic value of red cell distribution width (RDW) and N-terminal pro B-type natriuretic peptide (NT-proBNP) for short-term clinical outcomes in acute heart failure (AHF) patients has not been fully investigated.A total of 128 patients with AHF were enrolled and followed for 3 months. Primary endp...

journal_title：International heart journal

authors： He W,Jia J,Chen J,Qin S,Tao H,Kong Q,Xue Q,Zhang D

更新日期：2014-01-01 00:00:00

abstract：:Several studies have revealed that stress after catastrophic disasters can trigger cardiovascular events, however, little is known about its association with the occurrence of heart failure in past earthquakes. The objective of the present study was to determine whether the Great East Japan Earthquake on March 11, 201...

journal_title：International heart journal

authors： Suzuki H,Yamada S,Kamiyama Y,Takeishi Y

更新日期：2014-01-01 00:00:00

abstract：:The aims of this study were to quantify the geometrical differences in left ventricular (LV) dyssynchrony in patients with heart failure (HF) using cine-tagged MRI, and to investigate the relationship between dyssynchrony and major adverse cardiac events (MACE) in HF.In 67 patients with HF [mean LV ejection fraction (...

journal_title：International heart journal

authors： Nagao M,Yamasaki Y,Yonezawa M,Kamitani T,Kawanami S,Mukai Y,Higo T,Yabuuchi H,Sunagawa K,Honda H

更新日期：2014-01-01 00:00:00

abstract：:The purpose of this study was to clarify the effect of standing balance training on walking speed (short-term outcome) and cardiac events (long-term outcome) in elderly ischemic heart disease (IHD) patients. This was a retrospective cohort study. Ninety-two elderly (≥ 65 years) IHD patients who underwent an inpatient ...

journal_title：International heart journal

authors： Yamamoto S,Matsunaga A,Wang G,Hoshi K,Kamiya K,Noda C,Kimura M,Yamaoka-Tojo M,Masuda T

更新日期：2014-01-01 00:00:00

abstract：:Coronary artery spasm after coronary artery bypass surgery may result in life-threatening arrhythmias, circulatory collapse, or death. We report two cases of coronary artery spasm after coronary artery bypass surgery, one of which developed ventricular fibrillation requiring extracorporeal membrane oxygenation support...

journal_title：International heart journal

authors： Unai S,Hirose H,Cook G,Lee Y,Miura S,Kigawa I,Fukuda S,Miyairi T

更新日期：2014-01-01 00:00:00

abstract：:Epicardial adipose tissue (EAT) is presumed to play an important role in the development of coronary artery disease (CAD). The purpose of our study was to examine the influence of EAT volume measured by cardiac CT on the severity and presence of CAD. A total of 209 subjects (114 normal subjects and 95 patients with CA...

journal_title：International heart journal

authors： Kim SH,Chung JH,Kwon BJ,Song SW,Choi WS

更新日期：2014-01-01 00:00:00

abstract：:Vaccines are commonly used as a preventive medicine for infectious diseases worldwide, however, clinical trials on an amyloid beta vaccine for Alzheimer's disease represents a new concept in the field of vaccinations. Several recent studies indicate the potential of therapeutic vaccines as well as classical vaccines a...

journal_title：International heart journal

authors： Nakagami H,Koriyama H,Morishita R

更新日期：2014-01-01 00:00:00

abstract：:The 5-hydroxytryptamine2A receptor antagonist sarpogrelate hydrochloride exerts its effect not only by inhibition of platelet aggregation, but also by some pleiotropic effects. We have reported that a low serum lipoprotein lipase (LPL) mass level reflects insulin resistance and may be a risk factor for atherosclerotic...

journal_title：International heart journal

authors： Nagayama D,Ohira M,Saiki A,Shirai K,Tatsuno I

更新日期：2014-01-01 00:00:00

abstract：:Catheter ablation has been established to be an effective therapy for drug-refractory paroxysmal AF and is recommended as the treatment of choice for many patients, including those with a permanent pacemaker (PM). However, the clinical efficacy of catheter ablation of paroxysmal AF in patients with a permanent PM for ...

journal_title：International heart journal

authors： Wu JT,Dong JZ,Wang SL,Chu YJ,Wang LX,Yang CK

更新日期：2014-01-01 00:00:00